On the occasion of the annual retreat of the Interdisciplinary Centre for Neurosciences (IZN) of the University of Heidelberg at Schöntal Monastery on 10 July 2017, Constanze Depp was presented with the Foundation BrainAid IZN Master's Award. With this prize, which was awarded for the first time this year by the BrainAid Foundation, the selection committee chaired by Professor Christoph Schuster (University of Heidelberg) honoured Constanze Depp's work on the connection between calcium signals and oxidative damage to mitochondria. In her Master's thesis at the Institute of Neurobiology at the University of Heidelberg, supervised by Dr Carlos Bas Orth, Ms Depp was able to clarify how synaptic activity and the associated change in neuronal gene expression lead to mitochondria being protected from oxidative stress. These findings make an important contribution to the understanding of neurodegenerative processes in the brain.